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Risk of early mortality and cardiovascular disease in type 1 diabetes: A comparison with type 2 diabetes, a nationwide study

Cardiovascular Diabetology Nov 24, 2019

Lee YB, Han K, Kim B, et al. - Using Korean National Health Insurance Service datasets of preventive health check-ups from 2009 to 2016, researchers analyzed data of 20,423,051 individuals (≥ 20-year-old) without baseline cardiovascular disease in order to estimate hazard ratios of myocardial infarction (MI), hospitalization for heart failure (HF), atrial fibrillation (AF), and mortality in adults with type 1 diabetes vs those without diabetes and those with type 2 diabetes. During follow-up of more than 93,300,000 person-years, 116,649 MIs, 135,532 AF cases, 125,997 hospitalizations for HF, and 344,516 deaths were reported. The type 1 diabetes group had higher fully-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for incident MI, hospitalized HF, AF, and all-cause death within the mean follow-up of 4.6 years than the type 2 diabetes [HR (95% CI) 1.679 (1.490–1.893) for MI; 2.105 (1.901–2.330) for HF; 1.608 (1.411–1.833) for AF; 1.884 (1.762–2.013) for death] and non-diabetes groups [HR (95% CI) 2.411 (2.138–2.718) for MI; 3.024 (2.730–3.350) for HF; 1.748 (1.534–1.993) for AF; 2.874 (2.689–3.073) for death].
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