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Risk of developing metachronous advanced colorectal neoplasia after polypectomy in patients with multiple diminutive or small adenomas

The American Journal of Gastroenterology Nov 01, 2019

Kim NH, Jung YS, Lee MY, et al. - Researchers examined the risk of metachronous advanced colorectal neoplasia (ACRN) among patients with multiple diminutive or small adenomas. Based on baseline adenoma characteristics, they classified 9,733 patients (mean age: 45.8 ± 8.2 years) who underwent ≥ 1 adenoma removal and follow-up colonoscopic surveillance into following groups: group 1, 1–2 nonadvanced adenomas (NAAs)(n = 8,051); group 2, ≥ 3 diminutive NAAs (n = 293); group 3, ≥ 3 small NAAs (n = 258); and group 4, advanced adenomas (AAs) (n = 1,131). Outcomes revealed no differences in risk of metachronous ACRN among patients aged ≥ 50 years who underwent polypectomy of ≥ 3 diminutive NAAs, ≥ 3 small NAAs, and AA. This finding thus supports current guidelines recommending a uniform surveillance interval for these lesions.
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