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Risk of cancer in patients with fecal incontinence

Cancer Medicine Sep 06, 2019

Adelborg K, et al. - Researchers used Danish population-based registries and examined patients with hospital-based diagnoses of fecal incontinence in order to determine the risk of selected cancers, including colorectal cancer, other gastrointestinal cancers, hormone-related cancers, and lymphoma, in these individuals. This study included overall 16,556 patients with fecal incontinence. After 1 year, these patients had a cumulative incidence of less than 0.4% for colorectal cancers, other gastrointestinal cancers, hormone-related cancers, and lymphoma each. It increased to under 3% following 10 years. In this study, fecal incontinence was identified as a marker of cancer, particularly gastrointestinal cancers and lymphoma within 1 year, which probably is driven partially by reverse causation. However, low absolute risks were reported. The increased short-term risk of colorectal cancers may be partially explained by heightened diagnostic efforts.
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