Chamberlain AM, Boyd CM, Manemann SM, et al. - Experts ascertained differences in comorbid situations in individuals with heart failure contrasted with population controls and examined whether differences exist by type of heart failure or age. The prevalence of 17 chronic situations was obtained in 2,643 individuals with incident heart failure from 2000 to 2013 and controls matched 1:1 on gender and age from Olmsted County, Minnesota. Individuals with heart failure had a greater prevalence of many chronic situations than controls. Comparable correlations were noted in individuals with decreased and preserved ejection fraction, with the exception of hypertension, which was more robustly correlated with heart failure with preserved ejection fraction. Overall, some cardiometabolic risk factors were more firmly correlated with heart failure in younger persons, highlighting the significance of optimizing the prevention and treatment of risk factors and, especially cardiometabolic risk factors.