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Risk factors for falls, falls with injury, and falls with fracture among older men with or at risk of HIV infection

Journal of Acquired Immune Deficiency Syndromes Jul 02, 2019

Erlandson KM, et al. - Given a common occurrence of falls and fall risk factors among people living with HIV (PLWH), researchers examined men (aged 50–75 years) both with (n=279) and without HIV (n=379) from the Bone Strength Substudy of the Multicenter AIDS Cohort Study for fall risk factors. They noted ≥1 fall in 114 (41%) PLWH and 149 (39%) of uninfected men; ≥2 falls were observed over 2 years were seen in 54 (20%) PLWH and 66 (17%) of uninfected men. Low physical activity, detectable HIV-1 RNA, use of efavirenz, or use of medications to treat diabetes and depression were the risk factors recognized for recurrent falls or fall with a fracture. They recommend prioritizing interventions that focus on modifiable risk factors, including increased physical activity, antiretroviral therapy adherence, and transition off efavirenz in reducing fall risk.

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