Risk factors for atypical forearm fractures associated with bisphosphonate usage
Injury Oct 22, 2020
Cha SM, et al. - A retrospective case-control study was conducted to evaluate the diagnostic factors for atypical forearm fractures additional to atypical femur fractures. A complete enumeration survey for patients under the treatment of bisphosphonate (BP) was performed. Between March 2009 and February 2019, researchers distinguished 53 individuals that met the following inclusion criteria: a BP therapy history or ongoing administration of at least 1 year, presence of simple radiographs of bilateral femurs and forearms, and availability of complete medical records and radiological data. The outcomes demonstrated that the atypical forearm fractures are probably more common than reported in the literature to date, and all forearm lesions were accompanied by preceding atypical femur fractures. It was noted that the period of BP administration had the main impact on the occurrence of atypical forearm fractures, especially whether more than 65 months. Also, for forearms lesion, the prescription by multiple physicians was a predicting factor additionally to AFFs, nevertheless, a more evidence-based study is required to understand the impacts of cancer-related BP usage on the forearm.
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