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RIKADA study reveals risk factors in pediatric primary cardiomyopathy

Journal of the American Heart Association Jul 29, 2019

Al-Wakeel-Marquard N, et al. - Researchers investigated clinical risk factors in pediatric primary cardiomyopathy in this prospective study- the RIKADA (Risk Stratification in Children and Adolescents with Primary Cardiomyopathy) study. They carried out in-depth phenotypic and genetic characterization of 60 index pediatric patients with primary cardiomyopathy (median age: 7.8 years) and their first-degree family members (n=124). The factors that showed association with adverse outcome and therefore are recommended to be considered for risk assessment in pediatric primary cardiomyopathies were: lower body surface area, increased N-terminal pro–brain natriuretic peptide, left ventricular dysfunction or dilatation, late gadolinium enhancement, and increased number of variants of interest.
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