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Right atrial pressure predicts mortality among LVAD recipients: Analysis of the INTERMACS database

Heart, Lung, and Circulation Dec 02, 2020

Guglin M, et al. - Researchers analyzed pre-left ventricular assist device (LVAD) haemodynamic parameters in predicting post-LVAD mortality, and for this purpose, they used the INTERMACS dataset. They assessed the ability of right atrial pressure, pulmonary capillary wedge pressure, pulmonary arterial systolic and diastolic pressures, mean pulmonary artery pressure, transpulmonary gradient, cardiac output, cardiac power output and INTERMACS profiles, all documented prior to LVAD implantation, to predict death. Findings revealed that weak predictors of mortality were: haemodynamic variables, as well as other criteria including INTERMACS profiles. In LVAD recipients, the main consistent haemodynamic predictor of death was right atrial pressure. It performed better than other haemodynamic parameters, and also kept its worth within each INTERMACS profile.

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