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Rhythm control vs rate control in patients with atrial fibrillation and heart failure with preserved ejection fraction: Insights from Get With The Guidelines—Heart Failure

Journal of the American Heart Association Dec 18, 2019

Kelly JP, DeVore AD, Wu JJ, et al. - Researchers used inverse probability weighted analysis to define contemporary treatments for rate vs rhythm control and subsequent results in patients with heart failure with preserved ejection fraction and atrial fibrillation. For this purpose, they used the Get With The Guidelines—Heart Failure (GWTG-HF) registry connected to Medicare claims data from 2008 to 2014. The definition of rhythm control included the use of an antiarrhythmic medication, cardioversion, or atrial fibrillation (AF) ablation or surgery. They defined rate control as the use of any combination of β-blocker, calcium channel blocker, and digoxin without proof of rhythm control. According to the findings, a lower risk of 1 year all-cause mortality was observed in relation to rhythm control in patients aged 65 and older with heart failure with preserved ejection fraction and AF.
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