Patel SV, et al. - Experts aspired to explore whether agreement between subjective interpretations of Scheimpflug tomography maps of corneas with Fuchs endothelial corneal dystrophy (FECD) was influenced by daily and hourly changes in corneal edema. In a randomized manner, Scheimpflug imaging pachymetry and posterior elevation maps of corneas with a range of severity of FECD were evaluated for the presence of three tomographic features of edema. For the classification of diseases, subjective analysis of Scheimpflug images in FECD is highly repeatable. Although small interpretation differences resulted from pathophysiological changes in corneal hydration and other factors clinically significant disparities in interpretation were rare and therefore unlikely to influence clinical decision-making.