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Relationships between blood pressure measurements and target organ damage: Data from the Korea Women's Chest Pain Registry

The Journal of Clinical Hypertension Oct 31, 2018

Kong MG, et al. - Using data from a nation-wide registry, researchers examined how four “target organ damage (TOD) parameters (left ventricular mass index [LVMI], the ratio of mitral peak velocity of early filling [E] to early diastolic mitral annular velocity [e′] at septal annulus [E/e′], estimated glomerular filtration rate [eGFR], and obstructive coronary artery disease [CAD]) were related to four blood pressure (BP) measurements (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP], and pulse pressure [PP]). The participants were 652 patients (471 women, 58.4 ± 10.5 years) with suspected CAD who had elective invasive coronary angiography (CAG). An association of E/e′ with SBP, MAP and PP was observed in multivariable analyses, which also revealed a relation of CAD with SBP and PP. LVMI and eGFR were not related to any of the BP measurements. Stronger associations of SBP and PP with E/e′ and CAD vs DBP and MAP were seen among patients undergoing elective invasive CAG.

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