Kim JH, Kim SE, Kim SH, et al. - By using enhanced depth imaging optical coherence tomography, researchers intended to determine if there is an association between coronary artery calcification and subfoveal thicknesses of individual chorioretinal layers in patients with subclinical atherosclerosis. The sample consisted of 193 patients (193 eyes). Study participants were divided into three cardiovascular (CV) risk groups based on coronary artery calcium (CAC) scores calculated from cardiac-gated computed tomography: low (CAC = 0; n = 77), intermediate (CAC = 1-300; n = 83), and high (CAC > 300; n = 33). According to this retrospective, non-interventional, cross-sectional study, no statistically significant changes were found in the segmented retinal layer thickness of the central macula. A significant association was found between higher CAC scores and subfoveal choroidal thinning in patients with subclinical atherosclerosis. In individuals of advanced age with subclinical atherosclerosis, prominent decreases in the subfoveal choroidal layer could provide a valuable biomarker for anticipating cardiovascular risk.