Kwon WY, Jung YS, Suh GJ, et al. - Regional cerebral oxygen saturation (rSO ₂ ) level did not differ significantly, at 72 hours, between out-of-hospital cardiac arrest (OHCA) survivors undergoing targeted temperature management (TTM) 36℃ vs 33℃. A significant link was found between low rSO ₂ levels, especially at 24 hours of TTM, and poor 6-month neurological outcomes in OHCA survivors; this association was true irrespective of target temperatures.

• Total 57 comatose OHCA survivors were randomly assigned to either a 36℃ or 33℃ group.

• Continuous monitoring of rSO ₂ was performed during 72 hours of TTM.

• No difference was seen in serial rSO ₂ levels for 72 hours of TTM between the two groups.

• rSO ₂ level at 24 hours yielded an area under the receiver operating characteristic curve of 0.800 for poor neurological outcomes.