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Quantitative comparison of microvascular metrics on three optical coherence tomography angiography devices in chorioretinal disease

Clinical Ophthalmology Oct 25, 2019

Lu Y, Wang JC, Zeng R, et al. - All individuals were scanned on each of three optical coherence tomography angiography (OCT-A) devices, ie, Optovue Avanti Angiovue, Topcon DRI-OCT Triton Swept-Source OCT, and Zeiss Cirrus 5000-HD-OCT Angioplex in order to review OCT-A microvasculature metrics on three accessible OCT-A platforms. Thirteen eyes of seven individuals with chorioretinal diagnoses were analyzed. No notable variation in the foveal avascular zone (FAZ) area across the three devices was seen. An important variation in the superficial capillary plexus (SCP) vessel densities (VD) between the OCT-A devices was observed. In comparison to both Triton and Angiovue, significantly greater DCP VD was seen with Angioplex. A comparison of image quality exhibited that the highest quality is provided by Angiovue, followed by Angioplex and Triton. In summary, core macular microvasculature metrics are now promptly available on a diversity of available OCT-A devices. Across all three devices in this study, while the FAZ could be certainly measured, important variations for the vessel density in both the SCP and deep capillary plexus were noted. As a result, clinicians should be cautious while contrasting microvasculature metrics across various devices when using individuals' data in multicenter research examinations and clinical trials.
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