Edwards AC, et al. - Researchers examined how pregnancy is associated with the risk of alcohol use disorder via analyzing data from longitudinal population-wide Swedish medical, pharmacy, and criminal registries. Pregnant women born between 1975 and 1992 (N=322,029) were compared with matched population controls, with female relatives discordant for pregnancy, and with pre- and postpregnancy periods within individuals. Outcomes revealed an inverse association of pregnancy with alcohol use disorder across all analyses. They observed substantially decreased rates of alcohol use disorder during pregnancy relative to the prepregnancy period within individuals, and these rated remained reduced during postpartum periods. These findings establish that even a severe condition such as alcohol use disorder is subject to the protective effects of pregnancy.