Progress towards lymphatic filariasis elimination in Ghana from 2000-2016: Analysis of microfilaria prevalence data from 430 communities
PLoS Neglected Tropical Diseases Aug 15, 2019
Biritwum NK, Frempong KK, Verver S, et al. - In 2000, a national program to eliminate lymphatic filariasis was started in Ghana, with mass administration (MDA) of the drugs ivermectin and albendazole as the key strategy. Reviewing district-level data on the history of MDA and outcomes of transmission assessment surveys (TAS), they assessed progress towards elimination that was made by 2016 for all endemic districts of Ghana. In addition, they sought for the microfilaria (mf) prevalence from sentinel and spot-check sites in endemic districts. All 98 endemic districts started MDA in 2001–2006; MDA was stopped in 81 by the end of 2016 after passing TAS and after an average of 11 rounds of treatment (range 8–14 rounds). The mf prevalence in sentinel sites was reduced below the 1% threshold in 81/98 endemic districts in Ghana due to the MDA program of the Ghana Health Services, yet higher prevalence than this threshold was observed in 15 communities within 13 districts (MDA ongoing by 2016) during the surveys in 2013 and 2014. An intensification of the interventions was recommended in these districts to achieve the WHO 2020 target.
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