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Prognostic value of the H2FPEF score in patients undergoing transcatheter aortic valve implantation

ESC Heart Failure Nov 26, 2020

Ludwig S, Pellegrini C, Gossling A, et al. - Researchers conducted this multicentre study to evaluate the prognostic value of the H2FPEF score in patients undergoing transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) and preserved left ventricular ejection fraction (EF). In total, 832 patients from two German high‐volume centres, who received TAVI for severe AS and preserved EF (≥ 50%), were identified for calculation of the H2FPEF score. For TAVI patients with preserved EF, the H2FPEF score acts as an independent predictor of adverse CV and heart failure outcome. A high H2FPEF score is correlated with the presence of paradoxical low‐flow, low‐gradient AS, the heart failure with preserved ejection fraction (HFpEF) in patients with AS. The H2FPEF score might be useful as a risk prediction tool in patients with preserved EF scheduled for TAVI by identifying patients in advanced stages of HFpEF.

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