Feng JF, Wang L, Yang X, et al. - In patients with esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy, researchers investigated the prognostic ability of lactate dehydrogenase (LDH) to albumin (ALB) ratio (LAR). In this retrospective study, 346 resectable ESCC patients who received curative surgery without neoadjuvant therapy were enrolled. Data reported that the mean value for serum LDH was 180 ± 62 U/L, for ALB it was 40.3 ± 5.3 g/L and for LAR it was 4.6 ± 1.8. Findings revealed that in resectable ESCC patients who received curative surgery without neoadjuvant therapy, the optimal cut-off value of 5.5 for LAR is a helpful prospective prognostic biomarker. A high level of LAR (>5.5) correlated with poor cancer-specific survival.