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Prognostic value of baseline sarcopenia on 1-year mortality in patients undergoing transcatheter aortic valve implantation

The American Journal of Cardiology Nov 05, 2020

Yoon YH, Ko Y, Kim KW, et al. - Researchers sought to report on the association between sarcopenia and clinical outcomes in patients who underwent transcatheter aortic valve implantation (TAVI) using data from the prospective ASAN-TAVI registry. Among a total of 522 patients with severe aortic stenosis who underwent TAVI (mean age: 79 years; 49% men), mean skeletal muscle index (SMI) was 41.3 ± 6.7 cm 2/m 2 in men and 34.1 ± 6.5 cm 2/m 2 in women. Findings from the multivariate analysis indicated independent correlation of low-tertile of SMI with mortality. Findings overall suggest that sarcopenia measured by SMI was significantly linked with an increased risk of 1-year mortality among patients who underwent TAVI. The groups with high-surgical risk plus low SMI tertile exhibited substantially higher all-cause mortality.

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