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Prognostic role of diastolic dysfunction in patients undergoing transcatheter aortic valve replacement

Catheterization and Cardiovascular Interventions Apr 20, 2020

Kampaktsis PN, Vavuranakis M, Choi DY, et al. - Researchers intended to better assess the role of baseline diastolic dysfunction (DD) on results following transcatheter aortic valve replacement (TAVR), via this single‐center retrospective study. Following the exclusion of patients with atrial fibrillation, mitral valve prostheses and significant mitral stenosis, they included a total of 359 consecutive TAVR patients. The participants were divided into severe vs nonsevere DD depending on the assessment of high left ventricular filling pressure. All‐cause mortality or heart failure hospitalization was the outcome measure. A mean follow‐up of 13 months was performed. In this work, experts focused on the role of baseline DD on results post-TAVR by considering the presence of mitral annular calcification. Severe DD was found to be related to raised all‐cause death or heart failure hospitalization but not independently of other structural parameters and recognized predictors of the outcome measure.

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