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Prognostic importance of mitral e′ velocity in constrictive pericarditis

European Heart Journal – Cardiovascular Imaging Jun 12, 2020

Yang JH, Miranda WR, Nishimura RA, et al. - Given a crucial role of increased medial mitral annulus early diastolic velocity (e′) in constrictive pericarditis (CP) diagnosis by echocardiography, and given the role of mitral e′ velocity as an indicator of underlying myocardial disease, researchers investigated the prognostic implication of mitral e′ for long-term death following pericardiectomy in patients suffering from CP. They analyzed 104 surgically verified CP patients who had echocardiography and cardiac catheterization within 7 days between 2005 and 2013. On the basis of clinical history of concomitant myocardial disease, the categorization of patients as primary CP (n = 45) or mixed CP (n = 59) was done. The independent link of medial e′ velocity and mean pulmonary artery pressure with long-term death after pericardiectomy was revealed in the multivariable analysis. Overall, findings revealed better outcomes in relation to increased mitral e′ velocity among patients with CP. The presence of a paradoxical distribution of the link between E/e′ and pulmonary artery wedge pressure was revealed in these patients but there was no direct inverse correlation between them.

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