Brant A, et al. - Researchers studied 177 male candidates to quantify the survival influence of prostatic urethral involvement in non-muscle-invasive subjects not upstaged at cystectomy between 2000 and 2016. They observed a higher incidence of intravesical therapy (84.6% vs 64.4%), multifocal tumor (90.8% vs 51.7%), as well as positive urethral margins (7.7% vs 0%) and ureteral margins (18.5% vs 5.1%) vs candidates without prostatic urethral involvement. Prostatic urethral involvement was determined to be an independent predictor of overall mortality on Cox regression and is associated with inferior survival in these patients.