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Prognostic implications of left ventricular myocardial work index in patients with ST-segment elevation myocardial infarction and reduced left ventricular ejection fraction

European Heart Journal – Cardiovascular Imaging May 28, 2021

Butcher SC, Lustosa RP, Abou R, et al. - Researchers investigated if lower values of left ventricular (LV) global work index (GWI) at baseline were related to a decrease in LV functional recovery as well as poorer long-term prognosis among patients with decreased LV ejection fraction (LVEF ≤40%) post-ST-segment elevation myocardial infarction (STEMI). Participants were 197 people (62 ± 12 years, 75% men) with STEMI managed with primary percutaneous coronary intervention and decreased LVEF. A greater likelihood of LVEF normalization at 6-month follow-up was observed in relation to higher values of LV GWI among people with an LVEF ≤40% post-STEMI. Additionally, lower values of LV GWI were identified to be independently related to elevated all-cause mortality at long-term observation, offering incremental prognostic worth over LVEF and minor incremental prognostic value over LV global longitudinal strain.

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