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Prognostic implications of global longitudinal strain by feature-tracking cardiac magnetic resonance in st-elevation myocardial infarction

Circulation: Cardiovascular Imaging Nov 14, 2019

Reindl M, Tiller C, Holzknecht M, et al. - In this study, researchers examined whether myocardial strain measured by feature-tracking-cardiac magnetic resonance (CMR) could assist in predicting clinical outcomes following ST-elevation myocardial infarction. In this observational study of 451 revascularized ST-elevation myocardial infarction patients, they performed comprehensive CMR investigations 3 (interquartile range, 2–4) days after infarction for determining left ventricular ejection fraction (LVEF), global longitudinal strain (GLS), global radial strain, and global circumferential strain as well as myocardial damage. major adverse cardiac events [MACE] event occured in 46 patients (10%) during a follow-up of 24 (interquartile range, 11–48) months. Patients with MACE exhibited impairment in all 3 strain indices. In these patients, they identified a strong and independent predictive value of GLS by feature-tracking-CMR for the occurrence of medium-term MACE. Importantly, the observations suggest the superior and incremental prognostic value of GLS to LVEF and CMR markers of infarct severity.
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