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Prognostic implications of baseline B-type natriuretic peptide in patients undergoing transcatheter aortic valve implantation

The American Journal of Cardiology Jun 19, 2020

Medranda GA, Salhab K, Schwartz R, et al. - Researchers performed this retrospective, observational, analysis from 2012-2019, to investigate whether baseline B-type natriuretic peptide (BNP) levels have utility for predicting short-term results after transcatheter aortic valve implantation (TAVI). Data on 1,297 low-risk, intermediate-risk and high-risk patients who had TAVI, were analyzed. Participants were split into those exhibiting baseline BNP levels above or below 500pg/ml. Findings revealed that a composite of inpatient stroke or mortality and a composite of 30-day stroke, death or readmission after TAVI were both independently predicted by baseline BNP levels, following adjustments for discrepant baseline features. A closer post-TAVI monitoring may ultimately be needed for those low, intermediate and high-risk patients who exhibit a baseline BNP of ≥500pg/ml.

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