Usui E, Mintz GS, Lee T, et al. - Researchers conducted the study for analyzing the characteristics and prognostic effect of healed plaque (HP) detected by optical coherence tomography (OCT) in non-culprit segments in treated vessels. OCT analysis involved HP having a different optical intensity with clear demarcation from underlying plaque, thin-cap fibroatheroma, and minimal lumen area. A total of 726 NCLs, defined as a plaque with > 90º arc of disease (≥ 0.5mm intimal thickness), length ≥ 2 mm, and location > 5 mm from the stent edges, were studied in 538 patients who had a percutaneous coronary intervention with evaluable non-culprit segments by OCT. It was noted that the prevalence of an HP was 17.8% per lesion and 21.9% per patient. At both a patient- and lesion-level, an OCT-detected HP in an NCL is a marker for future (mostly) stable non-culprit-related major adverse cardiac event.