Kanamori N, et al. - Researchers investigated the prognostic impact of aortic valve area (AVA) in 1,309 conservatively managed asymptomatic patients with severe aortic stenosis (AS) and left ventricular ejection fraction ≥50% in the CURRENT AS (Contemporary Outcomes After Surgery and Medical Treatment in Patients With Severe Aortic Stenosis) registry. According to AVA, the participants were classified into three groups (group 1: AVA >0.80 cm², N=645; group 2: 0.8 cm² ≥AVA >0.6 cm², N=465; and group 3: AVA ≤0.6 cm², N=199). The primary outcome measure was a composite of aortic valve-related death or heart failure hospitalization. Findings revealed incrementally higher cumulative 5-year incidence of the primary outcome measure with decreasing AVA (24.1%, 29.1%, and 48.1%). Overall, for the detection of those high-risk patients with asymptomatic severe AS who could benefit from early AVR, AVA ≤0.6 cm² showed potential utility as a marker.