Nishii N, Nishimoto T, Mizuno T, et al. - Researchers investigated if a higher mortality is seen among patients with severe left ventricular (LV) dysfunction undergoing transvenous lead extraction (TLE). Data of 200 patients who underwent TLE were analyzed, and the participants were stratified as cases with ejection fraction < 35% [severe LV dysfunction (SLVD) group] and cases with ejection fraction > 35% (non-SLVD group). In terms of major complications and clinical success rates, no significant between-group differences were found. More chances of requiring additional hemodynamic support were noted in patients with severe LV dysfunction. Survival rate at 30 days and 1 year post-TLE did not vary significantly between the groups. In multivariate Cox regression analysis, the factors that were identified as predictors for 1-year mortality were log brain natriuretic peptide and serum hemoglobin concentrations. Overall, findings showed comparable prognosis post-TLE between patients with and without severe LV dysfunction. However, patients experiencing severe LV dysfunction often needed additional hemodynamic support.