Händel MN, Cardoso I, Rasmussen KM, et al. - Researchers systematically reviewed the quality of previously published systematic reviews and meta-analyses that investigated the association between processed meat intake and cancers, type II diabetes (T2D), and cardiovascular diseases (CVD), alongside summarizing the results of these works. A Measurement Tool to Assess Systematic Reviews (AMSTAR) was used to assess the quality of systematic reviews and meta-analyses. For this work, eligible reviews were those that comply with two quality requirements: providing sufficient information on quality assessment of the primary studies and a comprehensive search. This review included 22 systematic reviews in total. The included reviews were of moderate quality as indicated by their AMSTAR score ranging from 5 to 8. Overall, there was generally lack of quality assessments of primary studies of the reviews; the systematic reviews reporting positive associations between processed meat intake and risk of various cancers, T2D and CVD were of moderate scientific quality, and the results from case-control studies suggest more often a positive association than the results from cohort studies. Due to the serious risk of bias and imprecision, the overall confidence in the evidence was very low across all individual outcomes.