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Primary adrenal diffuse large B cell lymphoma: A clinicopathological and molecular study from China

Virchows Archiv Jun 01, 2018

Zhang J, et al. - In order to gain a better understanding of the clinicopathological and molecular features of primary adrenal diffuse large B cell lymphoma (DLBCL), researchers retrospectively reviewed 14 Chinese patients with DLBCL who initially presented with an adrenal tumor by using immunohistochemistry, immunoglobulin gene rearrangement analysis, evaluation of Epstein-Barr virus status, and fluorescence in situ hybridization. They found that in most of these cases, primary adrenal lymphomas were non-germinal-center B-cell-like subtype DLBCLs; these tumors showed high proliferative activity and had a poor prognosis.
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