Willems S, Tilz RR, Steven D, et al. - Given that ventricular tachycardia (VT) management with catheter ablation leads to a decrease in VT recurrence among patients with implanted cardioverter-defibrillators (ICDs), researchers compared results of preventive VT ablation (done prior to ICD implantation in order to prevent ICD shocks for VT) and deferred ablation following three ICD shocks for VT among patients with life-threatening arrhythmias requiring ICD implantation in this prospective, open, parallel, randomized trial, named the Preventive Ablation of Ventricular Tachycardia in Patients with Myocardial Infarction (BERLIN VT) study. This inquiry was undertaken in 26 centers. Participants were patients having stable ischemic cardiomyopathy, a left ventricular ejection fraction between 30% and 50%, and documented VT. The participants were randomly allocated 1:1 to a preventive or deferred ablation strategy. Findings revealed that preventive VT ablation prior to ICD implantation, vs deferred ablation strategy, did not decrease mortality or hospitalization for arrhythmia or worsening heart failure during 1 year of follow-up.