Jordan M, et al. - Authors assessed the efficacy of fibrin sealant (FS) and tranexamic acid (TXA) administered topically in patients with a hip fracture treated with prosthetic replacement. They compared 3 interventions to reduce blood loss: 10 ml of FS, 1 g of topical TXA, both administered at the end of the surgery, and usual haemostasis (control group). Findings did not suggest a significant reduction in the use of TXA and FS administered topically prior to surgical closure in patients with a sub-capital femoral fracture undergoing arthroplasty, compared with a group that only received usual haemostasis.