Latimer RL, Shilling HS, Vodstrcil LA, et al. - Researchers investigated the prevalence of Mycoplasma genitalium (MG) in men who have sex with men (MSM) tested at each anatomical site, that is, at the urethra, rectum and/or pharynx via performing a systematical review and appraising published data. Ovid Medline, PubMed, Embase yielded 46 studies that met inclusion criteria; 34 of these described estimates of MG prevalence at the urethra (13,753 samples), 25 at the rectum (8,629 samples) and 7 at the pharynx (1,871 samples). Findings suggest a common prevalence of MG in MSM, particularly at urethral and rectal sites (5% to 6%). Symptomatic men had more common detection of MG at both sites, and HIV-positive men had more common detection of MG at the urethra. At pharynx, MG was not detected frequently. Site-specific estimates are comparable to those for chlamydia and will be valuable in informing screening practices in MSM.