Prevalence of impaired renal function in virologically suppressed people living with HIV compared with controls: The Copenhagen Comorbidity in HIV Infection (COCOMO) study
HIV Medicine Aug 02, 2019
Petersen N, et al. - Caucasian people living with HIV (PLWH; n = 598) who were virologically suppressed on antiretroviral treatment and did not have injecting drug use or hepatitis C were examined for renal impairment and its associated factors. Renal impairment was defined as one measurement of estimated glomerular filtration rate ≤ 60 mL/min/1.73 m2. For this work, researchers also included sex- and age-matched controls (n = 2,598) from the Copenhagen General Population Study up to November 2016. As per findings, low-risk virologically suppressed Caucasian PLWH exhibited a low prevalence of renal impairment, but compared with controls, it was significantly more prevalent. An independent association was observed between HIV status and renal impairment after adjustment. In addition, renal impairment was observed in strong correlation to older age, female sex, and diabetes.
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