Ribeiro S, et al. - Researchers undertook the first study examining the prevalence and the determinants of both chlamydia and gonorrhea infections in men who have sex with men (MSM) in Portugal. For this cross-sectional study, they used data from 1832 visits to CheckpointLX, a community-based center for screening blood-borne viruses and other sexually transmitted infections (STIs) in MSM. The sample had chlamydia or gonorrhea prevalence of 16.05%, with 14.23% coinfection and 40.73% asymptomatic presentation among those testing positive. For chlamydia, anorectal infection was most common (67.26%), followed by urethral (24.78%) and oral (19.47%) infection. For gonorrhea, oral infection was most common (55.63%), followed by anal (51.25%) and urethral (17.50%) infection. Multivariate analyses revealed an independent association of young age, being foreign-born, reporting STI symptoms, inhaled drug use and having a higher number of concurrent or total sexual partners with higher rates of chlamydia or gonorrhea infection. Although no guidelines on chlamydia and gonorrhea screening exist in Portugal, results suggest a necessity for greater awareness about the importance of high-frequency screening for those at increased risk (ie, every three to six months).