Polkinghorne KR, et al. - Using the CKD Epidemiology Collaboration (CKD-EPI_eGFR) and Berlin Initiative Study 1 (BIS1_eGFR) eGFR equations in the ASPirin in Reducing Events in the Elderly (ASPREE) trial cohort of healthy older participants, researchers determined the baseline prevalence and predictors of chronic kidney disease (CKD). They defined CKD as eGFR <60 mL/min/1.73m² or ≥60 mL/min/1.73m² with urine albumin creatinine ratio (UACR) ≥ 3 mg/mmol. Analysis of data of 17,762 participants was performed; mean age was 75.1 years (SD 5); 56.4% were female, 76.4% had hypertension, 9% had diabetes mellitus. Prevalence of CKD with CKD-EPI_eGFR was 27% and doubled using the elderly specific BIS1_eGFR, with most participants reclassified from stage 2 to stage 3a. They noted an increased CKD prevalence in association with older age, hypertension, diabetes, or increased body mass index.