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Prevalence of carotid stenosis following radiotherapy for head and neck cancer: A systematic review and meta-analysis

Head & Neck Feb 24, 2020

Texakalidis P, et al. - By performing this inquiry following PRISMA guidelines, researchers determined the prevalence, incidence, as well as the degree of carotid stenosis among patients with a history of head and neck irradiation. They analyzed a total of 19 studies involving 1,479 patients. They found that the prevalence of carotid stenosis > 50%, > 70%, and carotid occlusion was 25%, 12%, and 4%, respectively. The cumulative 12-month incidence of carotid stenosis > 50% was estimated to be 4%, the 24-month and the 36-month was 12% and 21%, respectively. During the first 3 years after radiotherapy, a rise was evident every year in the yearly incidence of carotid stenosis > 50%. Based on the findings, routine yearly Doppler ultrasound screening starting 1 year following head and neck radiotherapy was advised by the experts.
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