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Prevalence and intensity of Schistosoma mansoni infection in pediatric populations on antiretroviral therapy in north-western Tanzania: A cross-sectional study

BMJ Open Jul 30, 2019

Mazigo HD, et al. - In a paediatric population on antiretroviral therapy (ART) in north-western Tanzania, researchers identified the prevalence and intensity of Schistosoma mansoni infection. This cross-sectional study involved 134 children (median age of 10 years). Data reported that the overall S. mansoni prevalence based on the Kato-Katz technique and point-of-care circulating cathodic antigen rapid test were 10.7% and 33.8%, respectively, and the overall geometrical mean eggs per gram of faeces was 293.9 GM-epg. Investigators found that paediatric populations on ART are co-infected with S. mansoni infection. It is suggested to screen and treat intestinal schistosomiasis at the initiation of ART to decrease the danger of developing the hepatosplenic disease and the detrimental impacts of schistosomiasis on the outcome of ART. The largest proportion of children on ART were infected with low intensity and a small proportion were infected with moderate to heavy intensity.
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