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Prevalence and factors associated with suboptimal peak inspiratory flow rates in COPD

International Journal of COPD Mar 07, 2019

Ghosh S, et al. - In a stable COPD population, researchers determined the prevalence of peak inspiratory flow rate (PIFR) discordance and associated clinical factors. The study sample consisted of 66 outpatients with COPD. Using the In-Check™ Dial with applied resistance of prescribed inhalers, PIFR was measured. The results obtained from the observational, single-center, cohort study indicate that PIFR is reduced in stable COPD patients, the only factor consistently associated with reduced PIFR being female gender. Discordance with prescribed inhalers has been observed in 40% of COPD patients, implying that many COPD patients do not generate sufficient inspiratory force to overcome prescribed resistance to DPIs during normal use. No association was found between PIFR by In-Check™ dial and PIFR measured by standard spirometer.
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