Premature ventricular complex site of origin and ablation outcomes in patients with prior myocardial infarction
Heart Rhythm Aug 26, 2020
Penela D, Teres C, Fernández-Armenta J, et al. - Researchers examined data on premature ventricular complex (PVC) ablation among post-myocardial infarction (MI) patients. A prospective study of 332 patients with frequent PVCs and left ventricular dysfunction was carried out. They compared data from 67 patients with previous MI vs the remaining 265 patients. At 12 months, a reduction in PVC burden from 29% ± 12% at baseline to 4.6% ± 7% was noted in post-MI patients, along with improvement in left ventricular ejection fraction from 33.6% ± 8% to 42% ± 10% as well as in New York Heart Association functional class from 2.1 ± 0.7 to 1.4 ± 0.5 points. Overall, in post-MI patients, a significant improvement in cardiac function and functional status was afforded by PVC ablation. Experts noted that PVCs mainly originated from MI scar and left ventricular outflow tract. A papillary muscle site of origin was identified to be strongly related to previous MI.
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