Pregnancy outcomes in women with autism: A nationwide population-based cohort study
Clinical Epidemiology Dec 06, 2018
Sundelin HEK, et al. - In women diagnosed with autism, researchers evaluated the risk of adverse pregnancy outcomes. In this nationwide population-based cohort study, 2,198 births of women diagnosed with autism in the Swedish National Patient Registry were compared with 877,742 singleton births of women without this diagnosis. Maternal autism was linked to preterm birth (defined as <37 completed weeks of gestation), probably because of an increased frequency of medically indicated preterm births (defined as preterm delivery after induction of labor or cesarean section before labor), but also because of other adverse pregnancy results, such as an increased risk of preeclampsia. In addition, maternal autism was not associated with emergency cesarean delivery, low Apgar score (<7), large for gestational age, gestational diabetes, and stillbirth, but with an increased risk of elective cesarean delivery and preeclampsia. The study findings suggested a need for extra surveillance during prenatal care.
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