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Predictors of Clostridium difficile infection and predictive impact of probiotic use in a diverse hospital-wide cohort

American Journal of Infection Control Sep 13, 2018

Carvour ML, et al. - Researchers performed a retrospective cohort study of adult hospitalized patients who were tested for Clostridium difficile infection (CDI) between May 1, 2011, and August 31, 2016, to assess the clinical and sociodemographic predictors of CDI using multivariable predictive logistic regression modeling. Outcomes revealed that independent predictors for CDI were Emergency Department location, high-risk antibiotics, probiotics, and statins. Findings support further exploration of the relationship between probiotics and CDI, especially in diverse patient populations.
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