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Predictive values of fasting glucose, postload glucose, and hemoglobin A1c on risk of diabetes and complications in Chinese adults

Diabetes Care Jun 07, 2019

Lu J, et al. - To evaluate the predictive ability of several glycemic measures for diabetes risk and complications, researchers assessed the correlations between outcomes and fasting plasma glucose (FPG), 2-hour postload glucose (2h-PG), and HbA1c using the cutoffs suggested by the American Diabetes Association’s 2010 criteria. During 2011–2012, baseline medical history, FPG, 2h-PG, and HbA1c were gathered from a population-based cohort of 193,846 adults (aged ≥40 years) in China. To evaluate incident diabetes, cardiovascular disease (CVD), cancer, and mortality, a follow-up visit was conducted during 2014–2016. During up to 5 years of follow-up, 8,063 cases of diabetes, 3,014 CVD-related events, 1,624 cases of cancer, and 2,409 deaths were documented. In models including FPG and HbA1c, 2h-PG independently predicts outcomes. In addition to FPG and HbA1c, routine 2h-PG testing should be considered to better evaluate outcome risks.

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