Zhou Y, et al. - In this retrospective analysis, researchers examined implantable cardioverter-defibrillator (ICD) patients to investigate the link between gamma-glutamyltransferase (GGT) and ventricular arrhythmias (VAs) in these subjects. This study included 140 patients with an ICDs; appropriate ICD treatment of ventricular arrhythmias (VAs) was the primary endpoint. Participants were followed-up for a mean duration of 44 ± 17 months. According to the findings, an independent association of GGT ≥56 U/L with VAs and cardiac death was evident in this ICD population. In Kaplan-Meier survival analysis, GGT ≥56 U/L was associated with increased VAs, ICD shock events and cardiovascular mortality. In multivariate COX regression models, GGT ≥56 U/L was an independent risk factor for VAs, ICD shocks, and cardiac death.