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Predictive score for identifying survival and recurrence risk profiles in patients undergoing ventricular tachycardia ablation

Circulation: Arrhythmia and Electrophysiology Dec 21, 2018

Vergara P, et al. - Researchers aimed to identify specific risk groups for mortality and ventricular tachycardia (VT) recurrence using the Survival Tree (ST) analysis method. Evaluating 16 demographic, clinical and procedure-related variables in 1251 patients as potential prognostic factors, they identified left ventricular ejection fraction, implantable cardioverter defibrillator/cardiac resynchronization device, previous ablation, in hierarchical order, as best predictors of VT recurrence, while left ventricular ejection fraction, previous ablation, Electrical storm as best predictors of mortality. They recognized 3 groups with significantly different survival rates: in the high-risk group, 65.0% patients survived and 52.1% patients were free from VT recurrence; within the medium- and low-risk groups, 84.0% and 97.2% patients survived, 72.4% and 88.4% were free from VT recurrence, respectively. They identified this study as the first of its kind that derived and validated a decisional model that provides estimates of VT recurrence and mortality with an effective classification tree.
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