Morales-Arraez D, et al. - Researchers examined patients with positive hepatitis C virus (HCV) serology for predictive factors for not undergoing RNA testing and the effect of implementing an automated electronic alert with recommendations in clinical practice. To remind physicians to test RNA following a positive HCV test and referral to specialist care, an automated alert notification has been employed since October 2014. Among 34,073 patients, 41,403 HCV antibody tests were requested and 870 (2.55%) patients tested positive. Observations revealed the feasibility of using an automated alert for recommending RNA testing after a positive HCV antibody test in clinical practice. In addition, the implementation led to increases in the rate of patients with RNA testing from 62.4% to 77.7%. Primary-care serology requests, no history of drug use, and a lack of social support were identified to be the independent predictors for not undergoing RNA testing.