Bae JH, et al. - In individuals with type 2 diabetes mellitus or normal glucose tolerance (NGT), the researchers studied the postprandial glucose-lowering effect of a premeal protein-enriched, dietary fiber-fortified bar (PFB), which contains moderate amounts of protein. For this analysis, study participants (15 type 2 diabetes mellitus and 15 NGT) were randomly assigned to either a premeal or postmeal PFB group and underwent two mixed meal tolerance tests, 1 week apart in reverse order. In both type 2 diabetes mellitus and NGT participants, acute administration of premeal PFB reduced postprandial glucose excursion. Findings revealed that premeal PFB augmented the early-phase insulin secretion, possibly through enhancing glucagon-like peptide-1 secretion in the type 2 diabetes mellitus participants.