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Posterior fossa decompression with or without duraplasty for patients with chiari type I malformation and basilar impression: A meta-analysis

European Spine Journal Oct 28, 2020

Cai S, Tian Y, Shen J, et al. - In this study, clinical effect and safety were compared between posterior fossa decompression with duraplasty (PFDD) and posterior fossa decompression without duraplasty (PFD) in the treatment of Chiari type I malformation and basilar impression. Researchers performed a comprehensive computer search from 2000 to 2019. Via the QUADAS-2 tool, the quality assessment was conducted. The pooled estimate of sensitivity and specificity were applied to assess the clinical value of comparison between PFDD and PFD. The study included a total of 468 individuals in 6 studies and ultimately met the eligibility criteria. In comparison with PFDD, PFD was found to be more efficient and safer therapy in the treatment of Chiari type I malformation with basilar impression.

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