Tang C, et al. - Authors evaluated the relationship between routine blood parameters and the effectiveness of neoadjuvant chemotherapy (NAC). Routine blood parameters and other clinicopathological data from 104 patients with locally advanced gastric cancer (LAGC) who received the oxaliplatin and capecitabine regimen as NAC were retrospectively collected from June 2010 to March 2016. A high objective response rate and pathological remission rate (pRR) was independently predicted by a low platelet-to-lymphocyte ratio and a high lymphocyte-to-white blood cell ratio in patients with LAGC treated with the oxaliplatin and capecitabine regimen as NAC. An independent predictor for a high pRR and long OS was high monocyte level, while a long OS and time to recurrence was seen in patients with high lymphocyte level.