Jaumdally SZ, Liebenberg LJP, Gumbi PP, et al. - Researchers sought to examine how partner serostatus influences disease progression in seropositive individuals. They investigated 337 HIV-infected heterosexual individuals in stable long-term HIV-seroconcordant or HIV-serodiscordant relationships. As per findings, HIV+ seroconcordant individuals vs their HIV+ counterparts in discordant relationships show higher frequencies of activated, CCR5-expressing T cells in blood and higher plasma viral loads and genital viral loads, which could translate to faster disease progression or larger viral reservoir.